A new study published last week in the New England Journal of Medicine points to undiagnosed cardiac disease as a contributing factor in Marathon deaths. While running marathons statistically is still very safe, there are usually a number of deaths every year worldwide. Doctors at some of the larger US Marathons have found that out of those who were resuscitated, many had consumed a couple of energy drinks loaded with caffeine that morning.
They advise that anyone training to run a marathon should visit their doctor to get a complete cardiac checkup before embarking on the 26.2 mile run. The International Marathon Medical Directors Association (IMMDA) also recommended taking a baby aspirin and limiting caffeine to less than 200mg on days of a long run to prevent sudden death. In that way a "susceptible" heart muscle won't be shocked and stop beating when the rush of adrenaline hits as the participant nears the finish.
If in doubt, consult your doctor.
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